cyberots

Eu tomo 400 mg por dia, nunca passei disso... no caso é uma caps mesmo. obs compre qq um menos Magnesium Oxide, é péssimo

Tem uma mais barata que essa super k da marca Vitacost, com 200mcg de mk-7 90 caps por 11 dólares... dá pra tomar uma cada 3 dias sim, vcprecisa de pelo menos 45 mcg/d.

Qualquer loja de 1,99 vc encontra um desses: Ou pra quem não quiser gastar 1,99

Eu já tomei e achei excelente rs vai de cada um..

Que bom, pensar que até outro dia vc era "do contra" rs bom saber que o tópico ajudou... abraços

Preço médio da vitamina D no exterior 9,00~13,00 dólares 360 caps 5000UI e 12,00~25,00 dólares 360 caps 10.000 UI... qq coisa fora disso acho muito caro! Eu acho que vc falou sim rs mas td bem eu entendi o que vc quis dizer no final.. abraços edit: acho que o fato mais importante que essas pesquisas demonstram e que a maioria delas cita é a descoberta da existência de receptores de vit D tb nos músculos, assim como vários tecidos do corpo, mostrando que há uma relação vital importantíssima tb entre eles.

Ué a pesquisa que vc citou não sugere nada e nem sequer pesquisou nada ou concluiu algo rs Ainda afirma não existirem estudos a respeito, fez somente uma hipótese sobre uma classe de medicamentos... dê que vc quer que eu chame? : Nunca tive problema nenhum não, pode tomar tranquilo... atualmente to tomando 20.000. abraços

Citando algumas coisas que achei rapidamente The effects of vitamin D on skeletal muscle function and cellular signaling. It is thought that every cell in the body expresses the vitamin D receptor, and therefore vitamin D may play a role in health and homeostasis of every organ system, including skeletal muscle. Human, animal, and cell culture studies have collectively shown that vitamin D affects muscle strength and function. Vitamin D functions in a plethora of cellular processes in skeletal muscle including calcium homeostasis, cell proliferation, cell differentiation, fiber size, prevention of fatty degeneration, protection against insulin resistance and arachidonic acid mobilization. These processes appear to be mediated by several signaling pathways affected by vitamin D. This review aims to explore the effects of vitamin D on skeletal muscle in each model system and to delineate potential cell signaling pathways affected by vitamin D. https://www.ncbi.nlm....pubmed/21397021 Vitamin D and Its Role in Skeletal Muscle Molecular mechanisms of vitamin D action in muscle tissue include genomic and non-genomic effects via a receptor present in muscle cells. Knockout mouse models of the vitamin D receptor provide insight into understanding the direct effects of vitamin D on muscle tissue. Vitamin D status is positively associated with physical performance and inversely associated with risk of falling. Vitamin D supplementation has been shown to improve tests of muscle performance, reduce falls, and possibly impact on muscle fiber composition and morphology in vitamin D deficient older adults. https://www.ncbi.nlm....45/?tool=pubmed Vitamin D and human skeletal muscle. Vitamin D deficiency is an increasingly described phenomenon worldwide, with well-known impacts on calcium metabolism and bone health. Vitamin D has also been associated with chronic health problems such as bowel and colonic cancer, arthritis, diabetes and cardiovascular disease. In recent decades, there has been increased awareness of the impact of vitamin D on muscle morphology and function, but this is not well recognized in the Sports Medicine literature. In the early 20th century, athletes and coaches felt that ultraviolet rays had a positive impact on athletic performance, and increasingly, evidence is accumulating to support this view. Both cross-sectional and longitudinal studies allude to a functional role for vitamin D in muscle and more recently the discovery of the vitamin D receptor in muscle tissue provides a mechanistic understanding of the function of vitamin D within muscle. The identification of broad genomic and non-genomic roles for vitamin D within skeletal muscle has highlighted the potential impact vitamin D deficiency may have on both under-performance and the risk of injury in athletes. This review describes the current understanding of the role vitamin D plays within skeletal muscle tissue. https://www.ncbi.nlm....pubmed/19807897 Vitamin D: extent of deficiency, effect on muscle function, bone health, performance, and injury prevention. Vitamin D deficiencyis increasingly being identified in children, adolescents, and adults. Primary production of the active form of vitamin D occurs via a photolytic reaction induced by ultraviolet radiation B. Vitamin D has important effects on bone and muscle as well as on the immune system. Isolation ofa vitamin D receptor on muscle cells has been accompanied by studies showing receptor polymorphisms and age-related functional changeswhich have an effect on muscle performance. Insufficient levels havebeen associated with increased risk of stress fractures, decreased muscle performance, and increased sick days. Although there is still debate about the appropriate levels of vitamin D, studies have suggested a minimal level of 32 ng/ml. Supplementation serves as an inexpensive option associated with reduction in both morbidity and financial costs. https://www.ncbi.nlm....pubmed/20945707 Vitamin D and skeletal muscle tissue and function. This review aims to summarize current knowledge on the role of vitamin D in skeletal muscle tissue and function. Vitamin D deficiency can cause a myopathy of varying severity. Clinical studies have indicated that vitamin D status is positively associated with muscle strength and physical performance and inversely associated with risk of falling. Vitamin D supplementation has shown to improve tests of muscle function, reduce falls, and possibly impact on muscle fiber composition and morphology in vitamin D deficient older adults. Molecular mechanisms of vitamin D action on muscle tissue include genomic and non-genomic effects via a receptor present in muscle cells. Genomic effects are initiated by binding of 1,25-dihydroxyvitamin D [1,25(OH)(2)D] to its nuclear receptor, which results in changes in gene transcription of mRNA and subsequent protein synthesis. Non-genomic effects of vitamin D are rapid and mediated through a cell surface receptor. Knockout mouse models of the vitamin D receptor provide insight into understanding the direct effects of vitamin D on muscle tissue. Recently, VDR polymorphisms have been described to affect muscle function. Parathyroid hormone which is strongly linked with vitamin D status also may play a role in muscle function; however, distinguishing its role from that of vitamin D has yet to be fully clarified. Despite the enormous advances in recent decades, further research is needed to fully characterize the exact underlying mechanisms of vitamin D action on muscle tissue and to understand how these cellular changes translate into clinical improvements in physical performance. https://www.ncbi.nlm....pubmed/18727936 https://www.ncbi.nlm....pubmed/20538161 Acho que muitas deles vão contra essa sua teoria então...

Em sequencia... "Based on current evidence, there is little reason to believe that the occasional use of NSAIDs will negatively affect muscle growth, although the efficacy for their use in alleviating inflammatory symptoms remains questionable. Evidence on the hypertrophic effects of the chronic use of NSAIDs is less clear. In those who are untrained, it does not appear that regular NSAID use will impede growth in the short term, and at least one study indicates that it may in fact have a positive impact."

Todo mundo já respondeu!

Primeiro essa pequisa está avalianto fármacos anti-inflamatórios bem mais poderosos. Segundo ou não entendi direito ou não vi nada de negativo, a não ser ele levantanto uma hipótese que possa haver prejuízo no longo prazo, mas nada conclusivo. O que não faltam são pesquisas sobre a D no sistema musculo-esquelético e seus benefícios, é uma das áreas mais pesquisadas sobre a vitamina. Dp eu posto algumas aqui. Obs: bom sabe que estão lendo realmente os trabalhos Abraços

Sim 100% das medicações pra essa finalidade são testadas dessa forma, incluindo os fármacos. Sobre a inibição da COX-2 tem alguma referência?

A CREAPURE por ex atende as exigências e legislação de diversos países sofrendo análises e testes não tem comparação com creatina animal, feita em fábricas de rações animal... pela lógica ração tb tem os mesmo ingredientes da comida humana, que tem de diferente lá? Proteínas, vitaminas, gorduras.. Muda a higiêne, contaminação

Aqui tem um tópico creatina x creatina (tds para humanos) https://www.hipertrof...as/#entry501692 isso vale pra todos aminoácidos, bcaa, leicina etc etc Experimentem cotar um produto na farmácia de manipulação e no mercadão por ex pra ver a diferença de preços (ácido cítrico por ex). onde está a deferença? grau de pureza! https://www.brinkzone...-your-creatine/

Sim e contaminantes dicyandiamida e a dyhydrotriazina podem ser ainda pior... grau de pureza pra que me refiro é "grau alimentício", "grau farmaceutico" usados em suplementos.

Tem uma grande diferença no grau de pureza, isso até em marcas pra humanos... mas tem uma diferença fundamental é que para humanos existe legislação específica que regula isso. Isso sem falar na questão da higiene. Pra mim pra cavalos é pra cavalos, pra humanos é pra humanos, até o fabricante diz isso

Cavalo dorme na merda, come as coisas do chão... para com isso kkkkkkkkkkkkk

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Realmente comprovação não existe, só não confio da mesma forma que não fonfio em algumas marcas mais baratas. qtos às brincadeiras espero que ninguem tenha se ofendido, é só zuera mesmo! Abraços

Tem esse tb será que é bom?

Tomo da Dymatize em pó. Tive muitas melhoras sim, sono BEM melhor e consequentemente passa o dia melhor tb. Além de tb é barato principalmente esse em pó, sem dúvida vale á pena usar. Ainda não pesquisei a fundo caso não haja problemas pretendo usar sempre!

Eu to tomando 2 gramas que é a sugestão de uso do rótulo tb não tive nenhum colateral

Vitamina D e inibição da aromatase. https://www.ncbi.nlm.nih.gov/pubmed/20156557

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