Livro De Bolso Da Insulina

[sleepsurfsex 87]

Como usar Insulina?

Que tipo usar?

Qual dosagem?

Qual refeição fazer após aplicação?

São essas e outras perguntas que serão respondidas nesse conjunto de artigos, retirado da antiga Beyondmass, vamos lá.

Insulin

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Insulin is a hormone produced in the pancreas which helps to regulate glucose levels in the body. Medically, it is typically used in the treatment of diabetes. Recently, insulin has become quite popular among bodybuilders due to the anabolic effect it can offer. With well-times injections, insulin will help to bring glycogen and other nutrients to the muscle.

In America, regular human insulin is available without a prescription by the name of Humulin R by Eli Lilly and Company. It costs about $20 for a 10 ml vial with a strength of 100 IU per ml. Eli Lilly and Company also produces 5 other insulin formulations, but none of these should be used by bodybuilders. Humulin R is the safest because it takes effect quickly and has the shortest duration of activity. The other insulin formulations remain active for a longer period and can put the user in an unexpected state of hypoglycemia.

Hypoglycemia occurs when blood glucose levels are too low. It is a common and potentially fatal reaction experienced by insulin users. Before an athlete begins taking insulin, it is critical that he understands the warning signs and symptoms of hypoglycemia. The following is a list of symptoms which may indicate a mild to moderate hypoglycemia: hunger, drowsiness, blurred vision, depressive mood, dizziness, sweating, palpitation, tremor, restlessness, tingling in the hands, feet, lips, or tongue, lightheadedness, inability to concentrate, headache, sleep disturbances, anxiety, slurred speech, irritability, abnormal behavior, unsteady movement, and personality changes. If any of these warning signs should occur, an athlete should immediately consume a food or drink containing sugar such as a candy bar or carbohydrate drink. This will treat a mild to moderate hypoglycemia and prevent a severe state of hypoglycemia. Severe hypoglycemia is a serious condition that may require medical attention. Symptoms include disorientation, seizure, unconsciousness, and death.

Insulin is used in a wide variety of ways. Most athletes choose to use it immediately after a workout. Dosages used are usually 1 IU per 10-20 pounds of lean bodyweight. First-time users should start at a low dosage and gradually work up. For example, first begin with 2 IU and then increase the dosage by 1 IU every consecutive workout. This will allow the athlete to safely determine a dosage. Insulin dosages can very significantly among athletes and are dependent upon insulin sensitivity and the use of other drugs. Athletes using hgh can thyroid will have higher insulin requirements, and therefore, will be able to handle higher dosages.

Humilin R should be injected subcutaneously only with a U-100 insulin syringe. Insulin syringes are available without a prescription in many states. If the athlete cannot purchase the syringes at a pharmacy, he can mail order them or buy them on the black market. Using a syringe other than a U-100 is dangerous since it will be difficult to measure out the correct dosage. Subcutaneous insulin injections are usually given by pinching a fold of skin in the abdomen area. To speed up the effect of insulin, many athletes will inject their dosage into the thighs or triceps.

Most athletes will bring their insulin with them to the gym. Insulin should be refrigerated, but it is all right to keep it in a gym bag as long as it is kept away from excessive heat. Immediately after a workout, the athlete will inject his dosage of insulin. Within the next fifteen minutes, he should have a carbohydrate drink such as Ultra Fuel by Twinlab. The athlete should consume at least 10 grams of carbohydrates for every 1 IU of insulin injected. Most athletes will also take creatine monohydrate with their carbohydrate drink since the insulin will help to force the creatine into the muscles. An hour or so after injecting insulin, most athletes will eat a meal or consume a protein shake. The carbohydrate drink and meal/protein shake are necessary. Without them, blood sugar levels will drop dangerously low and the athlete will most likely go into a state of hypoglycemia.

Many athletes will get sleepy after injecting insulin. This may be a symptom of hypoglycemia, and an athlete should probably consume more carbohydrates. Avoid the temptation to go to bed since the insulin may take its peak effect during sleep and significantly drop glucose levels. Being unaware of the warning signs during this slumber, the athlete is at a high risk of going into a state of severe hypoglycemia without anyone realizing it. Humulin R usually remains active for only 4 hours with a peak at about two hours after injecting. An athlete would be wise to stay up for the 4 hours after injecting.

Rather than waiting to the end of a workout, many athletes prefer to inject their insulin dosage 30 minutes before their training session is over and then consume a carbohydrate drink immediately following the workout. This will make the insulin more efficient at bringing glycogen to the muscles, but it will also increase the danger of hypoglycemia. Some athletes will even inject a few IUs before lifting to improve their pump. This practice is extremely risky and best left to athletes with experience using insulin. After the injection, they will consume a carbohydrate drink and then have breakfast within the next hour. Some athletes find this application of insulin very beneficial for putting on mass, while others will tend to put on excess fat using insulin in this way.

Insulin use cannot be detected during a drug test. For this reason, along with the fact that it is cheap and readily available, insulin has become a popular drug among the competitive athlete. However, before an athlete attempts to use insulin, he should educate himself and make himself aware of the consequences. One mistake in dosage or diet can be potentially fatal.

Directions for first time Insulin users (not sure who orginally wrote this one)

Insulin is the most anabolic hormone you can take. On the other hand its also one of the most dangerous for two reasons availability and ignorance. I will be the first to tell you that every time I have been hypoglycemic (when blood sugar drops to dangerous levels) its has been as a result of something I did wrong. Used responsibility and with respect for the potential sides it is quite safe and extremely effective. That being said we'll start off with what you are going to need.

Equipment:

There are several types of insulin out there but for our purposes we are only interested in two. The first being my favorite Humulin R and the other being a bit newer to the body building community Humalog.

Humulin R is the most widely used and time tested insulin in our arsenal. It has a max duration of 4hrs and its peak can been seen around 2hrs after injection. This becomes particularly important when planning out you meals for the day so keep the timetables in mind.

Humalog is a bit newer but some feel just as effective and a bit safer. Humalog has a max duration of 2hrs and its peak can be seen around 1hr after injection. When selecting to use one or the other keep in mind your schedule, meals, and physical activity for the day as it will all play a role. One other point that needs mentioning is that Humulin R is available over the counter at pretty much every pharmacy in the country for about $25 for 10ml (which will last you a very long time) and Humalog is available only through a prescription or over the black market for a price about double that of Humulin R. When approaching a pharmacist keep in mind that its a lot more convincing if you buy the needles at the same time you get the insulin. This way they are less likely to refuse to sell it to you which they have been known to do from time to time. If this should happen just continue on to the next pharmacy and despite what they tell you "you dont need a prescription" it might be their store policy to see one but legally it is not required and if you make enough of a fuss you will get what you need.

The next thing you will need is the actual needles for injection. These are not the same type that you would use for anabolics or other androgens. The type of needles you will need are U100 insulin needles. That is exactly what you need to say when are trying to buy them. A box of 100 will usually run about $15-$25 and again will last you quite a while. Be fore warned now, using a syringe labeled with cc/ml or anything other than u100 is potentially fatal. The difference between the amount of insulin used for our purpose and that which will kill you is less than 1/2 a cc.

The next two things I think you will need and I highly recommend having on you is a wrist watch with a chronograph (stopwatch) and glucose tabs and/or a can of soda. First I'll explain the wrist watch. The stop watch is to be started immediately after the injection and monitored periodically to keep track of what is in your body and how long it is active. This can also be used to determine whether or not you are feeling side effects or simply just nerves from the fear that follows using for the first time. For instance I always use Humulin R which we know has a duration of 4 hours and a peak at 2 hours. This means that the greatest effects will be felt somewhere between 1-1/2 to 2 hours after injection and then they will steadily lessen till it is no longer active 4 hours after injection. When you use a stopwatch you have an accurate record of when you felt the effects which will become more important as you get more experienced using insulin. The glucose tabs are your safety net. If you are feeling hypo (hypoglycemic) these tabs will return your blood sugar levels to a safe range where you can get some food. They are available at all pharmacies for about $1.00. I have also used a soda. Soda is high in simple carbs which act quickly when blood sugar is low and allow you to get to a safe range where you can get some food in you. Now that we've covered all the equipment needed to safely use insulin we'll move on to dosage diet and scheduling.

Dosage diet and scheduling:

Whenever you start insulin its always wise to start at a lower dose and taper up over the first couple of days of use. Insulin is still new in our community and there is a potential for becoming diabetic so dont take chances start small more is not better where insulin is concerned more is simply more fat and more dangerous. This is a schedule I use when just starting insulin:

day1: 5iu's post workout

day2: 6iu's post workout

day3: 7iu's post workout

day4: 8iu's post workout

day5: 9iu's post workout

day6: 10iu's post workout

day7: same as day 6

This concludes week once from here on out this is how I proceed. If I am going to be increasing my dose even further.

day8-10: 10iu's morning, 10iu's post workout

day11-14: 10iu's morning, 10iu's noon, 10iu's post workout

day15 and on: increase post workout dose till I start to feel symptoms of hypoglycemia and then back the dose down accordingly. THIS IS ONLY FOR ADVANCED USERS, DONT EXCEED THE DAY 7 DOSE TILL YOU GET SOME TIME UNDER YOUR BELT. I AM NOT KIDDING YOU WILL DIE!!!

Your diet will depend on the amount of slin you take per injection. The rule is 10 grams of carbs per IU of insulin. Therefore if you take 10iu's at an injection you need 100 grams of carbs. This is a bit overkill the actual figure is about 5-7 grams but its best to stick with the 10 rule while starting out. I feel that the best most accurate way to consume the proper amount of carbs after an injection is through MRP's or other shakes. The amounts of carbs on these are far more accurate than those you will find on the back of a bread bag. My meals are usually layed out like this:

7am: 10iu's insulin, shake

9am: shake

12pm: 10iu's insulin, lunch

2pm: shake

4pm: shake

6pm: workout

7pm: 10iu's insulin, shake, higher in carbs than others

9pm: dinner

11pm: safe for bed

If you'll notice there is a method to the madness above. After taking your first injection if insulin you will need a shake immediately. After this you are good for the next 2 hrs till the insulin peaks. Once you hit the 2hr mark you will need more carbs either another shake or a meal with sufficient carbs. After you have cleared the 4hr mark you will be clear from danger. Now this is all based on using Humulin R. If you are using Humalog you will need to take your first meal after injection and another "1hr" after. Then after the 2hr mark you will be safe. My shakes are made up of 1/2 pack of MetRX (berry) and 2 scoops GNC brand weight gainer (vanilla) and 16oz of whole milk. This shake has a caloric value of about 800 cals and around 50grams of protein and 150+grams of carbs. This is a good meal for those starting out. As you progress though you will want to decrease the carbs and eliminate the fat completely to maximize lean mass gains and minimize water and fat retention but for the purposes of starting out simply taking T3 will offset any fat gained. One thing to keep in mind is that T3 will reduce your sensitivity to insulin allowing you to take a higher dose but again save this till you get some more time in.

Side effects and procedures:

After injection and starting your stopwatch your first task is to get some carbs in. Next the first sides you will feel is tired. This is normal and is to be expected. You will usually feel this somewhere between 15-30 minutes after your injection. The key here is not to sleep, if you sleep you wont feel further more dangerous sides and therefore you wont be able to save your ass. The next thing you need to do is have another meal/shake at the 2hr mark. If you miss this just get it in as soon as possible. If you delay long enough you will start to feel hypo around 3 to 3-1/2 hours after injection. When this happens you will feel a sort of numbness that I can only relate to ephedrine. After this you will start to get some shakes in your hands followed by a cold sweat. Once you get to this point you are full blown hypo, the next thing that will follow will be a bit of tunnel vision and this is as far as I’ve been after this its all textbook I imagine coma will follow shortly after passing out. When you get the symptoms listed above don’t hesitate. Get some soda/glucose tabs followed by a meal or shake. One other fact I neglected to mention is that a mix of carbs is necessary when consuming a meal. Simple carbs are used to quickly and complex don’t kick in fast enough. A good mix is the way to go.

Insulin FAQ

What is insulin?

Insulin is a hormone secreted by the beta cells of the

pancreas that controls the metabolism and cellular uptake of

sugars, proteins, and fats. As a drug, it is used principally

to control diabetes. Insulin is not a steroid.

What type of insulin should I use for bodybuilding?

Humulin R and Humulog are the only insulins I recommend

because they act fast and are out of the body fastest(this

makes them the safest). I have never used Humalog but

understand that aside from quicker onset and half-life it is

essentially the same.

Why do I want to use insulin?

Insulin has been called "Anabolicus Maximus" by some gurus of

the bodybuilding world. Insulin can give you greater gains

than you have ever had using anabolics alone. Insulin, in

combination with androgens and resistance exercise, may

trigger maturation of satellite muscle cells (small, more or

less useless cells that are held in reserve, which do not

contribute to muscular strength) into mature muscle cells that

do contribute to muscular size and strength. How freakin cool

is that. Hyperinsulinemia has been shown to stimulate protein

synthesis in isolated limb infusion experiments , these anabolic properties seem to be the result of insulin binding

to IGF-1 receptors.

If insulin is so great why aren't all diabetics huge?

Diabetics have a disease and use insulin to replace endogenous

insulin that they cannot produce. Bodybuilders use insulin in

a totally different way. Some diabetic bodybuilders manipulate

their insulin use to use insulin for muscle growth and get

good results but changing dosages and times of injection of

insulin for diabetics can be dangerous.

Isn't taking insulin dangerous?

ummm YES! Before deciding to take insulin here is what you

have to do to be safe.

Insulin safety

1. Do not use slin alone have a training partner or girlfriend

who's not using slin hang around with you from the time you

take the slin to about 2.5/4 hrs after.

2. Tell you're partner to look for anything out of the norm

for your personality and have a list of questions like your

ssn or address etc that they can ask you. Don't joke around,

and answer them without ****, because if you cant answer or

refuse to answer it could be a sign of hypoglycemia(low blood

sugar). Symptoms of hypoglycemia include disorientation,

headache, drowsiness, weakness, dizziness, fast heartbeat,

sweating, tremor, and nausea.

3. If you cant/wont answer or are feeling the symptoms of

hypoglycemia they should be prepared to feed you carbs like

pancake syrup, coke, sugary stuff. I bought glucose tablets at

walmart. kinda like candy but gets in the blood faster and

dissolve quickly. these are for diabetics ask at the pharmacy.

4. Have your partner know that if they suspect low blood sugar

and cant convince or force you to consume carbs until your

better. CALL 911 and ask for an ambulance and tell the truth

to the operator... that they suspect you are in insulin shock

and explain when they get there(the ambulance guys not the

cops) that you are not diabetic but using insulin for anabolic

purposes. Have the type of slin, the dosage and carbs consumed

recorded to give the paramedic. They will save your life. Then

you refuse transport to the hospital and eat. It might be a

good idea to make sure your house is "clean" before every

workout just in case the bad thing happens and the cops ask a

lot of questions.

5. Why so much preparation for the possible problem?? insulin

can kill you in minutes if you go down!!

6. Take the carbs and protein together immediately after

injecting the slin(dont take chances trying to time out 15 min

after injection). Take the protein with the carbs because the

protein is pushed into the muscles with the slin also(creatine

too).

7. Before an hour passes you should eat a normal balanced

meal(high protein low fat with carbs).

8. Consume another small high protein medium carb low fat meal

at 2.5 hours after the injection. Congrats you lived.(keep

some gatoraid on hand just to make sure because your not gonna

have a lifeline)

9. YAWN... Don't go to sleep within 4/6 hours of using insulin

since you can develop hypoglycemia while asleep and not have

warning signs.

Ok I'm not scared I still want to use insulin...

Where do i get it?

Humulin R is over the counter (OTC) just about everywhere.

Humulog is new and is still a prescription drug is some

places. BUT... Insulin is NOT a controlled substance and will

not be confiscated by customs or postal inspectors so order it

online if you cant get it locally. Its legal.

Where do I keep it? (STORAGE)

The FDA requires that all preparations of insulin contain

instructions to keep in a cold place and to avoid freezing.

The refrigerator is a good spot. Unrefrigerated insulin can be

kept of 28 days as long as it stays in a cool and dark place.

Where/how do I inject insulin?

The best sites for insulin injection are in the subcutaneous

tissue of the abdomen(avoid the area close to bellybutton)

.Usually, you should not inject within 1 inch of the same site

within 1 month. The arms and legs can also be used, but

insulin uptake from these sites is less uniform. Insulin

should be injected subcutaneously only with a U-100 insulin

syringe. "B-D ultra-fine" insulin syringes are good. Insulin

syringes are available without a prescription in many states.

If you cant purchase the syringes at a pharmacy, you can mail

order them. Using a syringe other than a specific insulin

syringe is dangerous since it will be difficult to measure out

the correct dosage.

How much insulin should I take?

I recommend never using over 10IU. 10IU is enough to make you

grow.

In general Dosages used are usually 1 IU per 20 pounds of lean

bodyweight. So a 220lb bodybuilder with 9% body-fat would use

10iu of insulin(aprox200lb lean mass/20 = 10iu). But even

experienced insulin users shouldn't use max dosage at the

beginning of an insulin cycle. First-time users should start

at a low dosage and gradually work up. For example, first

begin with 2 IU and then increase the dosage by 1 IU every

consecutive workout until you reach your calculated dose or

determine a maximum personal dose(some people are more

sensitive to insulin sides like hypoglycemia). This will allow

the athlete to determine a dosage he can safely use. Insulin

dosages can vary significantly among athletes and are

dependent upon insulin sensitivity and the use of other drugs.

Athletes using gh and thyroid might have higher

insulin requirements.

When do I take insulin?

It is my opinion that you should only take insulin after a

work out, never before or when not working out, because before

a work out you could crash and die during the workout and when

your not working out it makes you fat. Some people disagree

with this. IF you want, get some info from them and try it.

But remember I told ya so.

When do i eat after using insulin?

Immediately!!! DO NOT TRY TO TIME YOUR CONSUMPTION OF CARBS!!

You should immediately take a carbohydrate AND protein drink

after taking you're insulin. I've stated this twice because it

is very important. Even experienced insulin users can get a

surprise now and then.

Eat a meal at about an hour after using insulin. Consume

another small high protein medium carb low fat meal at 2.5

hours after the injection. keep some gatoraid on hand just to

make sure. Remember that insulin can still work much later so

be careful and eat if you feel hypoglycemia symptoms.

What do I eat after using insulin?

Some people recommend a zero fat intake for 4 hours after

taking insulin. I do not disagree with this. But if your

bulking you can be a little relaxed on this. But high fat

intake after taking insulin can lead to high body fat.

The carb/protein drink taken after the insulin shot should

contain AT LEAST 10 grams of carbs and 5 grams of quality

protein per IU of insulin injected with little or no

fat(creatine taken in this drink is optional but works great).

Before an hour passes you should eat a normal balanced

meal(high protein low fat with carbs). At 2.5 hours after the

injection you should Consume a small meal. keep some gatoraid

on hand just to make sure. Remember that insulin can still

work much later so be careful and eat if you feel hypoglycemia

symptoms. Once again i've stated this twice because it is

important.

***Some insulin users recommend far less carbs than I have

stated above. This is a personal decision you will have to

make since it could be very dangerous...Even deadly! My

opinion is to take the carbs and learn to diet after bulking

if you gain too much fat.***

How long should/can I take insulin?

Short cycles please because you could have side effects. It is

suspected that you could become an insulin dependant diabetic

but I have never seen proof, but is it worth the risk? I would

only use it a few times a week(maximum 4 on 3 off) for no more

than 3/4 weeks.

What should I avoid while using insulin?

Do not use alcohol. It lowers blood sugar, and you may

experience dangerously low blood sugar levels.

Do not change your workout in the middle of a cycle of

insulin. Changes in how much you exercise can change the

amount of insulin you can tolerate and maintain blood sugar

levels.

Do not take any recreational drugs at the same time as insulin

since they could mask symptoms of hypoglycemia.

Do not change the brand of insulin or syringe that you are

using without first talking to a doctor or pharmacist. Some

brands of insulin and syringes are interchangeable, while

others are not.

Do not use insulin if you are sick with a cold, flu, or fever.

These illnesses may change your insulin requirements..

Do not use any insulin that is discolored, looks thick, has

particles in it, or looks different from the way it looked

when you bought it.

Do not use OTC drugs that will cause drowsiness within 6 hours

of using insulin.

Do not go to sleep within 4/6 hours of using insulin since you

can develop hypoglycemia while asleep and not have warning

signs.

What are the possible side effects of insulin besides

hypoglycemia?

Rarely, people have allergic reactions to insulin. Seek

emergency medical attention if you experience an allergic

reaction (difficulty breathing; closing of your throat;

swelling of your lips, tongue, or face; or hives).

Hypothetically, one could become an insulin dependent diabetic

if insulin is used too long.

Fontes:

http://www.meso-rx.com/steroid-profiles/insulin.htm

"Taber's Cyclopedic Medical Dictionary," Copyright © 2001 by

F. A. Davis Co., Phil., PA

http://www.getbulky.com/Info/Steroid_Info/insulin.html

http://www.bodybuilding.com/fun/catinsulin.htm

Elisabeth R. Barton-Davis, Daria I. Shoturma, Antonio Musaro,

Nadia Rosenthal, and H. Lee Sweeney. Viral mediated expression

of insulin-like growth factor I blocks the aging-related loss

of skeletal muscle function. Proc Natl Acad Sci U S A

22;95(26):15603-7, 1998

http://www.subscriberx.com/.SRX?Ser...Dialect=English

http://www.rxlist.com/frame/display.cgi?drug=HUMULIN

http://www.lillydiabetes.com/Produc...ityProfiles.cfm

Insulin: The Most Anabolic Hormone

Look back through picture archives of bodybuilding and you will be struck by a startling fact. In the last half-decade bodybuilders have been getting much larger much quicker. Certain professionals have added twenty pounds to their contest weight in one season, after having seemingly reached a plateau. The bodybuilding audience loves to hear that this weight gain is due to some secret drug or some newly discovered gene therapy. Elaborate theories are developed to explain these rapid weight gains and the professionals themselves are not helpful; they claim that it's the new X-brand supplement that's doing it and leave it at that.

The truth is that bodybuilders have discovered the most anabolic hormone produced by the body, insulin. Additionally, insulin has the benefit of being not only legal and over the counter in most states, but it is very cheap. A bottle costs less then thirty dollars and there is no need to worry about counterfeits. By correctly using insulin, in conjunction with human gh and anabolic steroids , modern professionals have added pounds of mass onto seemingly stagnant physiques.

This chapter will give a brief overview of insulin and the methods by which its anabolic action is exerted. We will outline how to correctly and safely use insulin both to gain size and to prepare for a contest (or simply diet).

Insulin: The Overview

Insulin is a peptide hormone, secreted by the pancreatic islets of Langerhans. Insulin promotes glucose utilization, protein synthesis, and regulates the metabolism of sugar. Insulin travels until it reaches receptor sites on cells. At these sites insulin facilitates the transport of glucose and amino acids across the cell membrane to be used inside the cell for energy and protein synthesis. This is insulin's anabolic effect, not only in super-saturating the cells with nutrients, but also helping to volumize the cell.

Insulin Safety:

There are significant risks that accompany the use of insulin. The greatest risk is an over-dose of insulin, which leads to hypoglycemic shock. This is not an overdose in the typical sense of the word; in this case it means that too much insulin was administered for the amount of glucose in the bloodstream. To this end, it is important to choose the correct type of insulin and to know when it peaks and the effective period of action of the drug in your body. This information is provided later in this chapter.

The symptoms of insulin shock are easy to recognize.

Distress is relatively rapid, usually in a matter of minutes.

Hunger.

Sweating.

Cold, clammy feeling.

Paleness.

Trembling, anxiety.

Rapid heartbeat.

Feeling of weakness or faintness.

Irritability and change in mood or personality.

Loss of consciousness.

Treatment:

Feed the person a source of quickly absorbed sugar. If the person is conscious, table sugar, fruit juice, honey, a non-diet soft drink, or any other available sugar source will do. If the person is unconscious, do not try to force sugar or liquid down his throat. Honey, granulated sugar, or a special capsule (such as D-glucose) containing concentrated sugars, which some diabetics carry, can be carefully placed under the tongue where it is absorbed into the body. However, this may be difficult to do.

There is another rapid form of intervention that anyone using insulin should know about; a glucagon pen. Injectable glucagon is a hormone, normally produced in the pancreas, which has effects opposite to those of insulin. It is commonly used to treat hypoglycemia or low blood sugar. It may also be used to relax parts of the gastrointestinal tract for certain examinations. It is not a controlled substance. In the event of the onset of hypoglycemia, this emergency injection will pull your blood sugar back up. If you are using insulin, you should have one of these pens with you at all times.

Take the person to a hospital emergency room as quickly as possible. Severe insulin reactions can be fatal. Do not be afraid of getting into "trouble", the use of insulin is legal. You will certainly get a lecture about how crazy it is to use insulin, but you will not be arrested or detained in anyway.

It is extremely important to have someone who you can trust monitor you when you are using insulin. They should be aware of the signs of insulin shock as well as the course of action to follow in the event that you do slip into a hypoglycemic state. Some insulin users will go so far as to purchase a medic alert bracelet that indicates them as a diabetic in the even that they pass out in public.

During a bulking phase, when calorie intake is deliberately high, insulin shock is not likely to be a problem assuming that post injection nutrition is precise (as outlined later in the chapter). In the even that you begin to feel any of the above symptoms immediately begin to consume the most simple sugars you can find, particularly look for glucose polymers and dextrose. Avoid fructose, as it is ineffective at raising blood sugar levels rapidly.

In the even that you are using insulin in dieting, do not be afraid to "blow your diet" by eating candy if you feel your blood sugar getting dangerously low. Your diet is not worth your life.

Types of Insulin:

There are three important characteristics that differentiate the available types of modern insulin. To properly use insulin in bodybuilding it is important to know the following characteristics:

Onset:

the time it takes the injected insulin to reach the blood stream and begin to work.

Peak:

the time period in which the insulin is working it's hardest to lower the blood sugar.

Duration:

the length of time the insulin will be working in the bloodstream. It is important to remember that insulin is an indiscriminate storage hormone. It doesn't care if its storing fat or glucose. Therefore fat intake should be as low as possible during the effective period of the insulin in the body. This will help prevent excessive fat gain.

For bodybuilding purposes we will only be concerned with three types of insulin; Humalin "R", Humalin "N" and Humalog are the most useful types of insulin. The other varieties are mixes of the above types in set ratios.

Humalin "N" is the longest acting insulin; it is active in the body for 24 hours. Additionally, it peaks several times throughout the day. Humalin "N' is useful in the high calorie off-season when there will always be an abundant supply of glucose. However, even the most dedicated bodybuilder who is eating many small meals may run into serious trouble in the insulin peak corresponds to a period of low blood sugar. Also, the long duration of Humalin "N' means that the bodybuilder must adhere to a low fat diet throughout the day, which is incongruously with the eating necessary to achieve brutal size.

Humalin "R" is known as the rapid insulin. The manufacturers claim that this type of insulin is active in the body for up to six hours; in reality it's closer to four and a half hours. The onset time of "R" is roughly thirty minutes and the drug peaks in one and a half to two and a half hours after injection.

Humalog is the fastest acting insulin. It has duration of about 2 hours, peaks in fifteen minutes, and is ideal for bodybuilding purposes because it is out of the body quickly. The speed at which Humalog works is beneficial because it allows us more precise control and lets us know exactly when food needs to be consumed.

Insulin Injection Procedure:

Insulin can be injected intravenously, intramuscularly, or subcutaneously. Injection insulin into the veins is creepy, but safe. However, it is not necessary to do this, as injection insulin into muscle or under the skin is just as effective.

The injection site, exercise, and the accuracy of the dosage measurement, the depth of injection and by environmental temperatures, can affect insulin absorption. To obtain consistency in daily insulin absorption and action, you should vary injection sites within the same anatomical region. The abdomen provides an excellent area for consistent absorption of insulin, whereas the leg and arm areas are often affected more by exercise. Repeated injection in the same area may cause a delay in absorption whereas massaging the site of injection may lead to an increased rate of absorption. Insulin should be injected at a 90-degree angle using an insulin syringe (25 unit, 30 unit, 50 unit, or 100 unit size) or with an insulin pen. If redness, pain, or lumps are noted at the injection site, this area should be avoided until the problem goes away.

Be sure to follow proper sterilization procedures. Wipe down the injection area with alcohol. The insulin needle is very thin so bleeding should be minimal. However, press a swab of cotton soaked in alcohol over the injection site after you withdraw the needle. This will protect almost entirely against infection.

An increase in blood flow to an injection site will increase the rate that insulin is absorbed. So, exercise will cause insulin to be absorbed more rapidly, because blood flow has increased to the exerted muscle groups. You will need to either inject less insulin or eat more carbohydrates after exercise. Rubbing the injected area increases blood flow, and hence, absorption.

Post Injection Meals and Supplements:

Depending on the onset time of the insulin type you are using you have varying lengths of time in which to ingest the post-insulin meal. Generally your post insulin meals should follow these guidelines.

60-80 grams of a good quality protein powder. Whey protein is ideal. This is taken immediately after the injection.

7 grams of simple carbohydrates (not fructose as it does not raise blood sugar quickly enough) per IU of insulin injected. Every 15-20 minutes after the first shot, take a few glucose tablets. This is will increase the amount of glucose available to your body for storage.

200 mg of chromium picolinate (this is optional).

200 mg of lipoic acid (this is optional).

30 mg vanadyl sulfate (this is optional).

2000 mg of hydroxy citric acid (this is optional).

5-7 grams of creatine monohydrate. This is crucial.

5-7 grams of glutamine powder. This is also crucial.

The total amount of insulin that you will be using daily is roughly 15-45 IUs depending on how many carbohydrates you can eat that day. During dieting periods, the total amount of insulin will be greatly reduced.

Typically, three injections of insulin are used daily. The first is taken immediately upon awaking; this is an appropriate time to use the Humalin "R". The second shot is taken mid-day and Humalog is recommended. The last injection is taken immediately after the workout of the day. If you are doing a double split training program, then take one shot after each workout and adjust your other injection accordingly. Do not take an injection too late at night; you want to be able to stay awake through the entire period of action so you can monitor yourself for signs of low blood sugar.

Anyone who is going to use insulin should take some time to familiarize him or herself with the glycemic index. The glycemic index is a ranking of foods based on how they effect the body's blood sugar levels. There are many resources that provide elaborate listing of many types of foods including fast foods. For our purposes it is merely important to identify the foods with high glycemic index scores to consume with the insulin injection. Below is a list of foods (or sugars) that scored very highly on the glycemic index.

Whole Foods or Candies

Jelly Beans

Dates

Sugar types

(in ascending order; Maltose elevates blood sugar the most)

Lactose

Honey

High fructose corn syrup

Glucose

Glucose tablets

Maltodextrin

Maltose

Conclusion

For many, insulin may seem like the perfect bodybuilding drug. It's legal, cheap, effective, and easy to obtain. However, the decision to use insulin is not one that can be made lightly. At worst, the misuse or abuse of anabolic steroids will probably result in no more than elevated liver enzymes and a host of undesirable cosmetic side effects. Improper use of insulin will result in much more serious consequences, including death. Bodybuilders must first ask themselves if they possess the necessary maturity and intelligence to responsibly use this hormone. Look before you leap my friends.

This chart show how long & how active the different types of slin are in the body.

Combinations:

INSULIN AND GROWTH HORMONE

Growth hormone (GH) is one of the most sought after bodybuilding drugs due to its' legendary abilities to strip off body fat and increase muscle mass. The former is accomplished through direct lipolysis (fat release from adipocytes), which GH does to an incredible degree. Muscle mass acquisition is accomplished through: the direct stimulation of protein synthesis, increasing amino acid uptake by muscle cells, and by greatly stimulating IGF-1 synthesis in the liver. It is this last point that is of interest to us because it is the main anabolic mechanism for GH, and it is also where insulin comes in to play. More than half of GHs' anabolic effect is due to IGF-1 production, but unfortunately this is quite often wasted. This is because IGF-1 has an extremely short half life in the bloodstream, so it usually doesn't reach many target tissues (muscles for our interest) to exert maximum anabolic effect. To rectify this situation, insulin can be used to increase the amount of an IGF-1 binding protein (specifically IGF1-BP3) that actually helps IGF-1 to reach the muscles and exert its' extreme anabolism. Insulin also reduces the amount of "bad" IGF1 BP's, (BP's 2 and 4) that would normally interfere with IGF-1 uptake and use by muscle. To say that there is a synergistic effect between insulin and GH doesn't do the combination justice. It makes me shudder to think of the hundreds of thousands of dollars spent on GH, without using it to the maximum anabolic potential. From a fat loss perspective, GH is incredible. It should directly negate the lipogenic effect of insulin, leaving you with one KICK ASS combination.

THE SKINNY ON INSULIN

There has been increasing popularity, and curiosity, concerning exogenous use of "the most anabolic hormone in the body". This makes it necessary to inform people how to maximise muscle mass acquisition and minimise horrid body fat accumulation when using it. The following is a detailed description of the effects of exogenous insulin use, combined with several other common bodybuilding drugs, from a muscle anabolism and fat catabolism point of view.

*WARNING*

Morons and bodybuilding novices should not consider insulin use, because it has one of the highest potentials for danger of all bodybuilding drugs. Its' use requires complete discipline and control over ones' environment. Insulin misuse should not be taken lightly because death's from it occur almost weekly. If that doesn't scare you, consider this: it can make you very, VERY, fat.

Before we delve in to the insulin alchemy, we should understand why insulin does such a good job of muscle and fat accumulation. Of course insulin is known as "the storage hormone", which means that it stores various macronutrients in different body tissues. Protein storage comes directly from amino acid uptake and protein synthesis in skeletal muscle. This is what we want. Fat storage comes from: directly reducing fat release from fat cells (adipocytes), increasing the rate at which the other macronutrients are converted in to fat, and inducing fat storage. This is what we don't want. Carbohydrate storage also occurs, but only significantly in special circumstances (discussed later). Now the fun part.

INSULIN AND ANABOLIC STEROIDS

Of course when everyone thinks of bodybuilding drugs anabolic steroids (AS) are the first things to come to mind, but how do they work with insulin? VERY WELL! AS decrease insulin induced fat accumulation through a number of ways. One is through creatine synthetase, which is an enzyme that goes crazy after workouts trying to store carbohydrates in the muscles (as glycogen, creatine phosphate etc.). For every gram of carbohydrate stored in muscle, roughly four grams of water go along with it (this is how creatine monohydrate achieves such dramatic results). How does this relate to insulin and AS? Well, the "harder" AS (exemplified by oxymethelone) increase creatine synthetase levels dramatically, giving insulin a place to do its' job and store carbohydrates. Okay, this also counts for a combined anabolic effect, but it prevents insulin from converting any "excess" carbohydrate in to fat (which would subsequently be stored)! AS also decrease levels of the main fat storage enzyme that insulin increases (called lipoprotein lipase). A big effect is through glucocorticoid antagonism, which means that AS indirectly increase insulin sensitivity (as well as act anti-catabolically). This allows insulin to bind to its' receptors more easily and accomplish its' job rather, than converting more macronutrients in to fat. Finally, the demand for nutrients by muscles is so high, in an AS enhanced state, that there is rarely any excess of nutrients to actually be stored as fat! A mere 400 mgs of enanthate didn't allow me to accumulate fat whether I was using insulin or not.

From a muscular anabolic perspective, there is a synergistic effect between AS and insulin. This is because they both directly stimulate protein synthesis as well as other mechanisms. One such mechanism involves AS hepatic mediated somatomedin release. Simply put: IGF-1 production in the liver. Again, the more powerful the AS, the more IGF-1 release, with orals having a much greater effect than injectables. Insulin increases the duration of time that IGF-1 is active in the bloodstream, and enhances receptor mediated IGF-1 activity (all through enhancing specific IGF-1 binding proteins). Another great combined effect is that insulin reduces the amount of Sex Hormone Binding Proteins (SHBP) in the blood stream. This allows more AS to be active and do their job of making you grow! Great effects were seen while using 10 units of insulin only three times a week, with AS. For the first few weeks of my next cycle I'm not going off the stuff, and I expect the effects to be scary!

INSULIN AND THE C/A/E(ECA) STACK

In case you've been living on Mars for the past few years, CAE stands for Caffeine, Aspirin, and Ephedrine. This stack has been shown to synergistically strip off fat, while preserving muscle mass. It is considered here because it is the minimum requirement, while using insulin, to prevent you from looking like the StayPuft marshmallow man. Also of benefit is that it is cheap and easily accessible. Using three times a day helps slow the fat accumulation, but strict dietary control is also necessary. The ephedrine: suppresses appetite, stimulates thermogenesis, and promotes and fat release from cells (beta receptor, and catecholamine, mediated), while the other two components of the stack increase thermogenesis by inhibiting certain enzymes and transmitters that try to slow down the thermic effect. Ultimately the appetite suppression effectiveness of ephedrine wears off, but this is replaced by a greater thermogenic effect (5-deiodinase, or Beta-3, mediated). The CAE stack does nothing for muscle anabolism in a hyper caloric situation, but that's what the insulin is for.

INSULIN AND CLENBUTEROL

This "soon to be classic" post-cycle stack not only increases muscle mass, but keeps fat off at the same time. Fat loss from clen is legendary for the first two weeks. After that time, the beta-2 receptors that it activates, attenuate (because of the extremely high binding specificity), dropping the fat burning effects to minimal levels. There should still be beta-1 receptor activation (which stimulates fat release from adipocytes) and beta-3 stimulation (the big thermogenic wonders), because they attenuate slower or not at all (respectively) compared to beta-2 receptors. Clen is a much better fat burner than ephedrine, due not only to its' higher receptor specificity, but also due to it's extremely long half life (the exact reason it's not approved for use in humans). This means that the drug is constantly burning fat, especially at night when serum glucose, and insulin, are low. Using aspirin and caffeine might slow the receptor attenuation, or at least increase the thermogenesis while its there (I can certainly attest to this!). Why hasn't anyone done this sooner? Clen, like AS, directly combats the fat storing enzyme that insulin promotes (lipoprotein lipase again) in white fat. However it actually increases this enzymatic activity in brown fat (hence the thermogenesis) and muscle. The latter event could promote muscle anabolism through a similar mechanism to HMB, or at least increases muscular fat storage (merely increasing muscle size). This may not seem significant, but the way that people are going nuts over synthol, you never know! The mechanism of action of clens' muscle building effect is not known, but it appears to be anti-catabolic rather than directly anabolic. It should be noted that this anticatabolism is not beta receptor mediated , and therefore does not attenuate. At any rate, the combined effect of the two drugs can be noticeable muscle gain while keeping fat off for the first two weeks. Can fat accumulation be slowed with this stack continue past this time? I'll let you know!

There has been increasing popularity, and curiosity, concerning exogenous use of "the most anabolic hormone in the body". This makes it necessary to inform people how to maximize muscle mass acquisition and minimize nasty body fat accumulation when using it. The following is the second article dealing with the effects of exogenous insulin use, combined with several other bodybuilding drugs and supplements, from a muscle anabolism and fat catabolism point of view. Part I outlined insulin use combined with: anabolic steroids, the C/A/E stack, and clenbuterol.

INSULIN AND GROWTH HORMONE

Growth hormone (GH) is one of the most sought after bodybuilding drugs due to its' legendary abilities to strip off body fat and increase muscle mass. The former is accomplished through direct lipolysis (fat release from adipocytes), which GH does to an incredible degree. Muscle mass acquisition is accomplished through: the direct stimulation of protein synthesis, increasing amino acid uptake by muscle cells, and by greatly stimulating IGF-1 synthesis in the liver. It is this last point that is of interest to us because it is the main anabolic mechanism for GH, and it is also where insulin comes in to play. More than half of GHs' anabolic effect is due to IGF-1 production, but unfortunately this is quite often wasted. This is because IGF-1 has an extremely short half life in the bloodstream, so it usually doesn't reach many target tissues (muscles for our interest) to exert maximum anabolic effect. To rectify this situation, insulin can be used to increase the amount of an IGF-1 binding protein (specifically IGF1-BP3) that actually helps IGF-1 to reach the muscles and exert its' extreme anabolism. Insulin also reduces the amount of "bad" IGF1 BP's, (BP's 2 and 4) that would normally interfere with IGF-1 uptake and use by muscle. To say that there is a synergistic effect between insulin and GH doesn't do the combination justice. It makes me shudder to think of the hundreds of thousands of dollars spent on GH, without using it to the maximum anabolic potential. From a fat loss perspective, GH is incredible. It should directly negate the lipogenic effect of insulin, leaving you with one KICK ASS combination.

INSULIN AND THYROID HORMONES

With the huge increases in fat mass often accompanying insulin use, it seems like a simple solution to use thyroid hormone. Unfortunately, this doesn't work out very well. The reason is that thyroid hormone (specifically T3 and possibly T4) increases the amount of the "bad" IGF1-BP's mentioned earlier;IGFBP2 and IGFBP4. This may not seem like a big deal if one is not using drugs to stimulate IGF-1 synthesis, but IGF-1 levels are naturally stimulated through acts like stretching, and even natural testosterone /GH increases. All of these things normally accompany workouts (if you know what you're doing), which is the best time to take insulin. So by having all of the free IGF-1 bound by IGFBP3s' evil siblings, much of the anabolic effect of insulin is lost! Since T3 (triiodothyronine) is the main culprit, does that mean that T4 (tetraiodothyronine) can be used with no detrimental effect? NO, because T4 is mostly effective by converting to T3, which leaves you with the same problem. In fact, T4 could very well do the same thing. So if you want to maximize the anabolic effectiveness of insulin while minimizing bodyfat accumulation, use another fat burner and leave the thyroid alone.

INSULIN AND CREATINE

These compounds may have an anti-synergistic effect on each other, meaning that the combined effect is less than the sum of the individual effects. This possibility exists due to both components' ability to store water in muscle cells. If only a certain amount of water can be stored in the cells through each mechanism of action, then the anti-synergistic condition would exist. Although this condition is unlikely, it is worth mentioning for future experimentation purposes (lab rats know where to contact me). One definite advantage of this combination is that creatine is best absorbed by the muscles when insulin serum levels are high, insuring maximum effectiveness. BTW-if one is not doing something as fundamental as using creatine , there is no way they should be using insulin (so basically insulin use requires creatine use).

INSULIN AND HCA

Getting straight to the point, unless you are a moron and are eating fat during insulin use, or you have crappy insulin sensitivity, HCA is the second most effective fat gain inhibitor next to clenbuterol (which is only more effective due to its' ridiculously long half life). Hydroxy Citric Acid (HCA) is the main ingredient in Citrimax, and is a bargain in terms of its': relative effectiveness (when using insulin), cost (cheap, cheap, cheap), and availability. It works by inhibiting an enzyme called ATP citrate ly(s)ase (ACL), which basically converts ingested carbs to fat (which insulin promptly stores). This is normally NOT a big deal since ACL levels are normally low in most humans. However, insulin drastically increases ACL levels (which should make sense based on what you now know about insulin) accounting for most of the, responsible use, fat gain associated with insulin use. This is the most exciting find since the discovery of insulin as an anabolic! Using insulin and not gaining fat while gaining muscle? What a concept! Although I don't like to go into the details of use directly, I believe it is warranted here. 500-750mgs HCA should be taken with or within half an hour after the insulin shot. The usually recommended 250mgs is ineffective in dealing with the drastic increase in ACL levels. The HCA is taken with the shot because both start to work on about one half hour, so the HCA can begin to be effective at the same time that insulin is trying to increase ACL levels. This regimen (only 3X500mgs HCA) prevented fat gain during a day when I used 3 separate insulin shots! To make things even better there is a mild glycogen storage property associated with HCA use. Since ingested carbs cannot be converted to, or stored as, fat, they are generally stored (due to insulin) as glycogen in muscle giving the user a mild but noticeable pump (similar to the first day of creatine use). To end this portion of the list, I give HCA my highest recommendation as the number 1 supplement to use with insulin!

INSULIN AND FLAX SEED OIL

Short and sweet. Don't use flax seed oil with insulin, because it is fat and *will* be stored. The fat storage rules totally change when insulin is involved (I even avoid vitamin E capsules because mine are oil based).

INSULIN AND CLENBUTEROL UPDATE

This may look like an ideal combination at first, but research has shown why my muscle gains with this combo were minimal. Clen reduces insulin sensitivity, which means that insulin will have a much harder time doing its' anabolic job on muscle tissue. In addition to storing amino acids as muscle, insulin also stores carbs in muscle (which gives a very "full" look to the muscles), which reduced insulin sensitivity also hinders. This is also combined with the fact that clen reduces Glut-4 transporters (which allow glucose passage, and subsequent storage, into muscle) in skeletal muscle which probably accounts for clens' ability to reduce muscle glycogen concentration. On a lighter note, the fat burning effects of clen are potentiated by aspirin and caffeine (through personal experience) but still die off after a few weeks. Overall the only time I would recommend this combination occurs when coming off a cycle and every bit of anabolism is needed, otherwise the two drugs have a bad effect (from an anabolic standpoint) on each other.

SIMPLE TIPS TO MAXIMIZE ANABOLISM AND MINIMIZE FAT GAIN WITH INSULIN USE

-USE HCA

- use testosterone enhancing compounds to increase hepatic IGF-1 production

- only use insulin first thing in the morning or during/after workouts

- don't consume *any* fat 2 hours before (due to digestion time) or one hour after (due to induced enzyme activity) insulin use

- stretch to locally increase IGF-1 levels

- continually eat protein spread over the 4-5 hour duration of insulin activity

Finally, my favourite tip from Docroid: (I) use one shot of insulin just before a one hour workout and another shot two hours after the first. This creates synergism between the activity of the two shots by the later shot increasing in activity at the same time as the first shot decreases in activity, giving one a steady high insulin level at the most important time for anabolism! The only time I can say that I have seen dramatic results from insulin use (in terms of muscle anabolism) occurs when I do this "technique". HOWEVER, this is *very* tricky, in terms of serum glucose levels, even for seasoned insulin users. After using for a while, one can get used to the "feel" of insulin, blood sugar crashes, feeding times etc. but things change when one has a high level of insulin for 3-4 hours straight. I've had to eat every hour for three hours during one of my first attempts at this technique, but every two hours some other attempts. This is the only time I don't feel secure with my own insulin use. It's actually a good thing I can now recognize what a blood sugar crash feels like or I'd probably be dead due to this technique. I don't recommend this technique to anyone (and if that's not a big deal to you, just remember who is writing this) but if you feel like using it, make sure that you have had a couple of, (horrible) insulin induced, serum glucose crashes so you can recognize the early warning signs for when you have them (and you *will* have them).

INSULIN AND ANDROSTENDIONE

This combo has potential due to the interesting ability of insulin to increase levels of 17B hydroxysteroid dehydrogenase(17B), which is the enzyme that converts andro. into testosterone. If the increase is anything near the 17B levels that women have, this could become the stack for "natural" Ïbodybuilders. Another possible benefit of this stack is the idea that insulin probably exhibits mild anti-aromatase properties. If this occurs to any significant level it could be great in increasing the 17B levels even more! Although I hate to rain on this theory parade, I have to say that I can't notice ANY anti-aromatase activity from insulin(see first update section). Other possible benefits of this stack are shown in the first part of this series under:

"INSULIN AND ANABOLIC STEROIDS". Of course any potential similarities with AS would be drastically minimized with andro. It should be noted that the term "natural" is used quite loosely.

INSULIN AND CAPTOPRIL

Captopril is an angiotensin converting enzyme(ACE)inhibitor. Its' medical function is to reduce blood pressure. The reason it is included here is because it can have great effects with insulin and AS. I wouldn't reccomend captopril to anyone unless you are hypertensive or are using AS, because it can drop blood pressure to a sub-normal level. A reason captopril is so great is because it increases endogenous growth hormone levels, which you know can be amazing, assuming you've read last month's article. Another benefit to captopril is its' decrease in protein urea(protein loss in urine). No other drug I'm aware of, including AS, GH, or insulin, does this. This means that there will be more protein for those other anabolic drugs to assimilate! Another great use of captopril is the fat loss effect it has. For me it removes the necessity of HCA while using insulin (with AS). Although I still use one 250mgs of HCA/day just for good measure, I could probably get away witho!ut it despite the extreme carb intake after a workout. On a more esoteric note, long term captopril use actually prevents the formation of new Alpha2 adregenic receptors, which would further potentiate fat loss. Also, water retention is minimized through captopril use, which ties into the blood pressure effects. A potential risk while using captopril with insulin is that both drugs do a good job of making one tired/sleepy. Add in a late night, high intensity workout and you'rer ready for bedtime. One can NOT fall asleep while using insulin or you would experience all of the dangerous side effects associated with its' use. A final warning about captopril is that it increases the retention of potassium which makes hyperkalemia (too much potassium)a possibility. Unexcessive intake of this electrolyte should allow for avoidance of any problems in most people. This stack really doesn't have any problems associated with it, as long as common sense is used. It is merely a matter !of responsibility to point out every potential problem, sim!ply so it can be avoided. It should be noted that beta agonists and even working out increase proteinurea.

INSULIN AND ANABOLIC STEROIDS UPDATE

I hyped up insulin and AS in the first article in this series and I don't take any of it back. Simply put: this combo rocks! Using these compounds I put on 10lbs in 4days! It wasn't fat or subcutaneous water so it had to be muscle! Okay, it was just intracellular water, but the results are still dramatic to say the least. Three 14IU shots a day keeps my body in a ridiculously powerful state of anabolism. I recommend that 100grams of easily digestible protein be consumed during the 4 hour duration of the drug (while juicing). At this time it can be assumed that every gram will be assimilated. My HCA use is down to every third shot of insulin, and that may be slightly unnecessary. Please note that I am also using captopril which exhibits fat loss characteristics. I have no other big tips to offer, except (I'd) use insulin as much as possible while on a heavy cycle. Since I'm getting gyno while using anti-estrogens, I have to say that the anti-aromatase ability of insuli!n is next to non-existent. I'd like to note that another AS/insulin user was also using GH and still gaining fat, although I don't know what his eating was like.

INSULIN AND BETA-AGONIST UPDATE

I now realize that the use of beta-andregenic agonists is useless while on insulin. They decrease insulin sensitivity and increase cortisol levels. Their fat loss abilities are overshadowed by the negative effects on insulin and anabolism. HCA should prevent any responsible use fat gain, making use of these compounds all the more futile. The only time I'd recommend clen and insulin is when coming off a cycle(I obviously don't buy the "clen is not anabolic" theory).

QUICK INSULIN USE TIP

Although nocturnal feedings are effective in keeping positive nitrogen balance, and decreasing the diurnal (daily) morning cortisol rush, they should not be used while using insulin during the day. These nocturnal feedings may prevent insulin sensitivity from improving as much as normal, which would lead to less anabolism and greater fat gain. The use of AS or doing insulin shots only after workouts negate this suggestion.

Artigo retirado da antiga www.nuclearnutrition.com

WHAT CAUSED THE HUGE SIZE GAINS MADE BY SEASONED PROS OVER THE PAST 5-6 YEARS??

A CANDID INTERVIEW WITH A TOP I.F.B.B. COMPETITOR

INTERVIEWS ARE A DIME A DOZEN AND CAN GO ONE OF 2 WAYS. THEY ARE EITHER COMPLETELY ****ING BORING WHICH IS THE KIND YOU READ IN THE MAGAZINES.....OR THEY ARE COMPLETELY FABRICATED, LIKE THE KIND YOU SEE ON OTHER BODYBUILDING

WEBSITES. THIS INTERVIEW REPRESENTS NEITHER. THE NAME OF THE INDIVIDUAL HAS BEEN KEPT ANONYMOUS DUE TO CONTRACTUAL OBLIGATIONS. WITH THAT BEING SAID, WHAT

IS TO FOLLOW IS A MOST INFORMATIVE AND EDUCATIONAL INTERVIEW ON ONE PARTICULAR TOPIC:

WHAT WAS THE CAUSE OF THE 20-30LB BODYWEIGHT JUMPS FROM 1994-PRESENT. I MEAN LETS FACE IT, NASSER EL SONBATY WAS AN AVERAGE PRO UNTIL 1995 AND RONNIE COLEMAN WAS A 2ND OR 3RD TIER ATHLETE UP UNTIL 1997, JEAN PIERRE FUX GAINED 40 LBS OF TISSUE IN A YEAR AND A HALF, CHRIS CORMIER HAS GONE FROM AVERAGE TO TOP 3, HELL EVEN DORIAN WENT FROM 230LBS TO 260LBS SEEMINGLY OVERNIGHT. ALL OF

THESE MEN HAVE HAD LOTS OF EXPERIENCE WITH STEROIDS AND G.H. SO THERE HAD TO BE ANOTHER FACTOR. AT FIRST IT WAS THOUGHT IGF-1 WAS RESPONSIBLE, BUT THIS PROVED TO BE A RATHER INEFFECTIVE COMPOUND.

SO WHAT WAS IT? WELL LET'S BEGIN THE INTERVIEW.

THIS QUESTION HAS BEEN ON EVERYONE'S MIND SINCE THE EMERGENCE OF 280-290LB BODYBUILDERS FROM SEEMINGLY OUT OF NO-WHERE. I ALWAYS THOUGHT IT MUST HAVE BEEN THE EMERGENCE OF IGF-1, BUT THEN AFTER RESEARCHING SOME THINGS, I FOUND OUT THAT IGF-1 IS A **** DRUG AND DOESN'T DO MUCH. WHAT GIVES?

I N S U L I N! THAT'S WHAT GIVES! I'VE KNOWN A LOT OF THESE GUYS FOR A WHILE NOW AND I CAN UNEQUIVOCALLY TELL YOU THAT IT IS THE RESULT OF INSULIN THAT THESE HUGE LEAPS HAVE BEEN MADE.

INSULIN? IF THAT IS THE CASE, THEN HOW COME SO MANY PEOPLE CLAIM IT WILL MAKE YOU FAT

BECAUSE IT CAN MAKE YOU FACT IF YOU DO NOT KNOW WHAT YOU ARE DOING AND DO NOT USE THE RIGHT TYPE.

CAN YOU EXPLAIN HOW TO USE IT SO ONE WOULD NOT GET FAT.

ACTUALLY IT'S QUITE SIMPLY. YOU SEE THERE ARE DIFFERENT TYPES OF INSULIN L, N, R , AND HUMALOG. THE DIFFERENCE IS IN THE ACTING TIMES. L LASTS IN THE SYSTEM FOR AROUND 24HOURS PEAKING SEVERAL TIMES THROUGHOUT THE DAY AND TAKES 2 HOURS TO BEGIN TO WORK, N IS MEDIUM IN ITS ACTING TIME LASTING AROUND 12 HOURS AND R IS THE QUICKEST OF THESE THREE, LASTING FOR ABOUT 6 HOURS AND HITTING THE

SYSTEM IN ABOUT 30-45 MINUTES. HUMALOG IS NEWER AND ACTUALLY BEGINS WORKING IN 5-15 MINUTES AND LASTS FOR 4 HOURS

ONCE YOU UNDERSTAND THIS, YOU CAN USE INSULIN TO YOUR ADVANTAGE. WITH ALL INSULIN YOU NEED TO HAVE GLUCOSE PRESENT IN THE BLOOD STREAM SO IT CAN HAVE SOMETHING TO ACT ON AND TRANSPORT IT INTO THE CELLS. THE POPULAR RULE OF THUMB OF 10-15 GRAMS OF GLUCOSE/CARBS PER I.U. OF INSULIN WAS SOMETHING THAT I ACTUALLY CAME UP WITH. PLEASE DON'T THINK I AM BEING ARROGANT, IT'S JUST THAT

I WAS DOING A LOT OF RESEARCH ON INSULIN IN THE EARLY 90'S AND IT IS DIRECTLY AND INDIRECTLY DUE TO THAT RESEARCH THAT INSULIN HAS BECOME A POPULAR TOOL IN THE BODYBUILDERS ARSENAL. MANY PEOPLE HAVE CONTACTED ME ON HOW TO USE INSULIN.

NOW WITH INSULIN YOU HAVE TO REMEMBER THAT IT IS AN INDISCRIMINANT CARRIER WHICH IS BOTH GOOD AND BAD. GOOD BECAUSE ALONG WITH THE TRANSPORTING OF GLUCOSE, IT WILL ALSO TRANSPORT AMINO ACIDS INTO THE MUSCLE CELLS. BAD BECAUSE IF THERE IS A LOT OF FAT PRESENT, IT WILL SHOVE THAT INTO THE CELLS AS WELL AND THIS IS WHY YOU GET FAT FROM INSULIN. IF YOU USE A LONG ACTING INSULIN THAT PEAKS SEVERAL TIMES THROUGHOUT THE DAY, IT IS IMPERATIVE THAT YOU EAT A CARB AND PROTEIN MEAL EVERY 2 HOURS TO INSURE THAT WHEN IT PEAKS, YOU HAVE A NUTRIENT POOL AVAILABLE FOR IT TO WORK ON. IF YOU TOOK A SHOT OF INSULIN IN

THE MORNING AND IT WAS LONG ACTING, IF YOU EAT A PIZZA AT 8:00PM, THE FAT WILL GET TRANSPORTED INTO THE CELLS AND YOU WILL GET FAT. THE WAY AROUND THIS IS TO 1. KEEP DIETARY FAT TO A MINIMUM ALL THE TIME OR 2. USE A FASTER ACTING

INSULIN. FOR ME--EVEN THOUGH I ALWAYS EAT LESS THAN 30GRAMS OF FAT PER DAY--THE ANSWER SHOULD BE 2.

THE REASON FOR THIS LIES IN THE FACT THAT YOU CAN CONTROL IT MUCH BETTER IF YOU KNOW THAT IT IS HITTING IN 15-20MINUTES AND WILL BE OUT OF THE SYSTEM IN 4 HOURS OR LESS. ALL OF THE INCIDENTS OF PEOPLE FAINTING OR GOING INTO COMAS BECAUSE OF INSULIN HAS TO DO WITH THE FACT THAT THERE WAS NOT ENOUGH GLUCOSE PRESENT IN THE BLOODSTREAM WHEN THE INSULIN PEAKED. WHEN YOU USE A LONG ACTING INSULIN THAT PEAKS AT VARIOUS TIMES OVER A 24HOUR PERIOD, YOU RUN A MUCH GREATER RISK OF NOT HAVING ENOUGH GLUCOSE PRESENT BECAUSE YOU ARE MORE APT TO SKIP A MEAL OR BE DRIVING IN YOUR CAR WHEN IT HITS...I LIKE THE HUMALOG THE BEST AND WOULD TELL EVERYONE TO USE IT SOLELY OR IF THEY CANNOT GET IT, USE

THE R. DO NOT USE THE N!

DOES IT MATTER WHAT TYPES OF CARBS YOU EAT WHEN YOU USE INSULIN?

YES! I AM A FIRM BELIEVER THAT YOU SHOULD USE PRIMARILY SIMPLE CARBS.

SIMPLE CARBS?

YES. LOOK AT THE END OF THE DAY THE BODY BREAKS DOWN COMPLEX CARBS INTO GLUCOSE AND IT IS GLUCOSE THAT IS TRANSPORTED INTO THE CELLS. WHEN YOU ARE USING A RAPID ACTING INSULIN IT IS IMPORTANT TO MINIMIZE THE TIME IT TAKES THE BODY TO CONVERT CARBS TO SIMPLE SUGARS. WHY CREATE ANOTHER STEP IN THE PROCESS? IT ONLY TAKES MORE TIME AND YOU RUN THE RISK OF NOT HAVING ENOUGH OF

THE COMPLEX CARBS BROKEN DOWN INTO GLUCOSE IN TIME WHEN THE INSULIN HITS. FOR THIS REASON I SUGGEST THE USE OF DEXTROSE.

SO WHAT IS THE REGIME YOU WOULD RECOMMEND?

WELL I SUGGEST THAT FOR OPTIMAL RESULTS, YOU USE HUMALOG AT 10-15IU'S IMMEDIATELY AFTER TRAINING BECAUSE THAT IS WHEN YOU BODY IS MOST DEPLETED OF GLYCOGEN STORES AND IS PRIMED TO OVERCOMPENSATE FOR THE INFLUX OF NUTRIENTS.

NOW HUMALOG HITS IN 5-15MINUTES SO YOU MUST IMMEDIATELY INGEST 10 GRAMS OF SIMPLE CARBS PER EVERY I.U. OF INSULIN YOU USE (IN THIS CASE BETWEEN 100-150 GRAMS) I WOULD ALSO TAKE IN ADDITIONAL NUTRIENTS THAT HELP CONTRIBUTE TO MUSCLE GROWTH SUCH AS AMINO ACIDS OR 50 GRAMS OF WHEY ISOLATE. I WOULD ALSO HAVE 5 GRAMS OF CREATINE AT THIS TIME TO AID IN CELL VOLUMIZING.

THE BEST CASE SCENARIO WOULD BE TO DO THIS TWICE AND DAY AND THE ONLY WAY YOU CAN DO THIS TWICE A DAY IS IF YOU TRAIN TWICE A DAY (THE MORE YOU DEPLETE YOUR GLYCOGEN STORES, THE MORE OF AN OPPORTUNITY YOU HAVE TO USE INSULIN TO OVERCOMPENSATE WITH NUTRIENTS)

WOULD YOU USE INSULIN DURING YOUR CONTEST PREP?

ABSOLUTELY I WOULD NOT PREPARE WITHOUT IT. YOU JUST HAVE TO KEEP IN MIND THAT YOU HAVE TO USE IT WHEN YOU CAN IN TERMS OF HIGH CARB AND LOW CARB DAYS WHEN YOU ARE DIETING.

SO LET ME GET THIS STRAIGHT. YOU ARE TELLING ME THAT INSULIN ALONE IS WHAT IS RESPONSIBLE FOR THE 20-30LB. JUMP IN LEAN BODY MASS IN ALL THE TOP GUYS?

ABSOLUTELY. I GUARANTEE THAT IF A BODYBUILDER IS STAGNANT AND HAS NOT USED INSULIN YET OR USED IT CORRECTLY, HE CAN PUT 20-30LBS OF MUSCLE ON. THERE IS NO DOUBT IN MY MIND. I AM SO SURE OF IT THAT I WOULD BET MY LIFE ON IT. I AM THAT POSITIVE.

ANYTHING ELSE ABOUT INSULIN WE SHOULD KNOW BEFORE WE MOVE ON?

YES. WHEN YOU USE IT, YOU WILL FIND THAT YOUR MUSCLES FILL OUT SO MUCH THAT YOU CANNOT USE IT EVERY DAY. I FIND THAT.

Reccomended pin for slin:

30 guage U-100 short needle (5/16 inch) I would get the 1/2cc syringes as it is much easier to accuratly dose your slin, they are marked from 1-30 or 50 units depending on the brand.

unlike the 1cc syringes.

Attached is the best pic I could find of these kind of pins.

Here is a good shake for post slin injections. No protein powder required.

16oz skim milk

2 cups of fat free yogurt I've used blueberry, strawberry, and key lime all were pretty good.

Blend together and drink, taste & texture is like the premade EAS myoplex shakes.

Fat 0 grams

Carbs 74 grams

Protein 36 grams

Add Protein powder if you want to take in more.

How To Use INSULIN Without Gaining Fat

Since Insulin is such a new subject for most of you the way I am going to do this post is going to be a little different. I am going to write a few sections on it then give links to a lot of different articles on the subject. I do not want to post a 10 page post that will just confuse you. My suggestion is to read this post and all the links then print out this post as instructions for your cycle. If you still have questions on this topic after reading it, let me know.

Insulin

Rating: 1-5 (Five being the highest)

4 Bulking

4 Cutting

2 Strength

n/a Testosterone Stimulation

n/a Use as an Anti-Estrogen

5 Side Effects

5 Ability to Keep Gains

Basic effects:

Increased workout Pumps

Increase in appetite

Increase the transport of nutrients into the muscle cells.

Side Effects:

Fat Gain

Hypoglycemia

Death

Stacking:

Creatine

Any roid

HGH

My first experience with Insulin:

About 2 years ago I tried insulin for the first time. I started using it 2weeks before my cycle to get use to it and figure out the best dosage for me. I worked up to using it at 10 units in the morning, 10 before I lift and 10 units after. I had a bout with Hypoglycemia only once but I felt pretty ****ty for a few days after. Anyway I stacked it with

40grams/day Creatine

750mg/week Sust

300mg/week EQ

The cycle lasted 10 weeks and I put on 40lbs, keeping 30 of it. This is what you can expect from you first bout with slin.

Section 1 - The right insulin to use and why:

There are various types of insulin available but as bodybuilders we are only interested in the short acting types. The only two types that should be used are Humalog and the R (Regular) Types. The difference between the two is the time it takes them to peak and the time to leave your system. In my opinion Humalog is the better choice for new users. There are a few reasons for this.

1. Humalog starts to work within 15 minutes after taking it

2. Humalog more closely matches the action curves of the insulin produced in your body then the R type.

3. Humalog does not last as long as the R type

All of these effects make Humalog easier to control then the R type.

Onset of action within 15 minutes 30 minutes

Peak effect 30-90 minutes 2-4 hours

Duration less than 5 hours 6-8 hours

Section 2 - How to obtain Insulin:

Insulin is over the counter in many states. The best was to obtain it is directly from a pharmacy. This way you know that it has been kept cold and did not lose potency. If you do not know if Insulin is OTC in your state then try this:

1. Call a pharmacy and tell them that you are from Florida and you are going to be coming to their area for a business trip for about 1 month. Tell them that you are a diabetic and you need to know if Insulin is sold with out a script their. Explain that since you live in FL you do not have a script since it is OTC. Also ask if insulin syringes are also sold OTC since some time one is but not the other. Also try this in any bordering state that is in driving distance.

The next way to get insulin is from an online pharmacy. You can usually order it and pins with out a problem. Hear is a list of sites that sell insulin and insulin syringes:

Section 3 - How to use Insulin for Beginners.

(Everything I will talk about will be using the R type since it is more available. If you can get Humalog email me if you have any questions on how to change your usage)

Now that you have your insulin let say you bought Humulin R. You need to make sure you have the right syringes. Insulin syringes are marked for units not CCs. 1 CC OF INSULIN WILL KILL YOU. So make sure you have the right type of syringes. You can order them from the sites above. Every CC of insulin has 100 units in it. When you Inject you can either Inject SubQ or Intra-muscular. Intra-muscular injections take effect about twice as quick.

Some basic rules:

1. Eat as much protein as you can plus 10grams of carbs per unit of insulin immediately after shooting the insulin.

5 units = 50 carbs

2. Keep some kind of simple carb on you at all times just incase you become hypoglycemic. A chocolate bar works well

3. Eat more protein and carbs about 2 hours after using the insulin. Around 5 grams of carbs per unit used of insulin.

4. Continually snack through out the rest of the day.

5. Try not to eat any fat for at least 4 hours after taking the insulin.

6. Try not to use insulin too late at night. You want most of it out of your system before you go to sleep

7. ***** Important ***** Be aware of the signs of Hypoglycemia:

? Shaking

? Vomiting

? headaches

? concentration problems

? visual disturbances

? muscle pain

? Weakness

? mood swings

? passing out

? Death

8. If you notice any of these signs immediately eat as many simple carbs as you can

9. Do not use any stimulants until you are use to how insulin effects you or you may mistake the signs of hypoglycemia for the effects of the stimulants.

When to take insulin:

As a beginner you should start by just taking it after working out. Start with 4 units and work up from there. Once you reach 10 units after working out try throwing in another 10 units when you wake up in the morning. I see no need to go much over 10 units at a time. I worked my way up to 20 units and all that did was make me hypoglycemic.

Hear is what your day should look like once you reach this point:

6am wake up

6:30 am Inject 10 units of Humulin R

6:31 am Eat a 12 egg white omelet and 3 waffles with enough syrup to = 100 carbs

8:30 am Drink a protein shake with at least 50 carbs in it

10:30 am an apple and a protein bar

12:30 pm Big lunch

2:30 pm Drink a protein shake (no carbs needed)

4:30 pm Snack

5:00pm workout

6:00 pm Inject 10 units of Humulin R (Assuming this is the end of your workout)

6:01pm Tuna salad with pasta and fat free mayo. (At least 100 carbs)

8:00 Drink a protein shake with at least 50 carbs in it

10:00 snack with some carbs

Before bed You should eat a good amount of carbs (50 or so) just to be safe

Insulin for Dieting:

Insulin can be used to get you into ketosis in 1 day. This really helps when doing any low carb diet. You will probably have to play around with the dosage to see what you need to get into ketosis.

This is what I do:

Eliminate carbs from your diet

Day 1 of the diet take 4 shots of insulin spaced 3 hours apart.

8am 2units of Humulin R

11am 2units of Humulin R

1pm 2units of Humulin R

3pm 2units of Humulin R

By the next morning I am deep into ketosis.

Why Insulin works:

Androgen/Insulin Synergy

By Michalovich Greutstein

Should anabolics be used with insulin or is it best to use insulin while off steroids in order to hold onto muscle mass?

We are going to demonstrate that they have to be used together. We will also try to provide some clues about their respective contribution to the synergy both hormones create. This will help us to handle both drugs better.

Here are some general observations:

It is safe to conclude something else is needed to uncover the full anabolic effect of steroids. The hormone which is the most affected by a high calorie or by a low calorie diet is insulin. Also, heavy steroid users know that past a certain amount of steroids, adding insulin will make a big difference as far as muscle gains are concerned. Insulin is thus a strong candidate as a potentiator of anabolic steroids(which we will indiscriminately refer to as androgens, steroids or anabolics). Furthermore, studies performed in trained dogs have shown a lack of insulin completely negates the anabolic effect of steroids on protein synthesis. There are some easy hypotheses such as a possible androgen receptor up regulation, a stimulation of androgen secretion, an antiaromatase effect arising from insulin. But, there is still something missing.

Using anabolics plus insulin will not make you much bigger unless you weight train. The synergy can only be realized if insulin + steroids + training are present. What is the link between those three factors?

A very likely candidate is an enzyme called insulinase. As its name implies, it is an enzyme responsible for the destruction of insulin. But we are going to see it does much more than that.

It is found inside many tissues of the body, particularly in muscle. What science is telling us is that insulinase is essential for insulin to provide its anti-catabolic effect on our muscles. It is also likely that insulinase is able to multiply the anabolic effects of androgens. It's worth repeating: insulin cannot stop protein catabolism without insulinase and the effects of steroids are potentiated by insulinase. It sure looks good.

Androgens are very powerful stimulators of the muscle protein synthesis rate. On the other hand, the muscle gains provided by androgens do not match this elevation in synthesis. steroids promote anabolism to a much higher rate than they make our muscles grow.

The reason for this discrepancy is that they also stimulate protein degradation. I know many people think they are anti-catabolic, but it is not the case. Anabolics stimulate protein turnover. This means they increase both synthesis and degradation of proteins. They are simply more effective at stimulating synthesis than degradation, which is why they make our muscles grow but not at a super fast rate. Look at how long it takes to grow huge muscles. If androgens were stimulating synthesis while inhibiting degradation, one would grow very, very quickly.

This is where insulin comes in. As we said, it mostly reduces protein degradation rate. It might stimulate protein synthesis right after training, but this effect is very limited in duration. Ideally, using insulin along with steroids would allow us to accelerate synthesis (thanks to anabolics) and reduce degradation (thanks to insulin). This is the best way to grow muscle fast.

Unfortunately, as both insulin and anabolics need insulinase to work better, they will compete against each other for this enzyme. For natural athletes, the supply of muscle insulinase should roughly meet the demand. Now if you add anabolics, there will be less insulinase for insulin. If you do not take too high a dose of steroids, the level of insulinase should still be sufficient to allow a fair insulin-induced anti-catabolism.

But as you take more steroids, the insulinase available for insulin will be lower and lower.

Insulin will lose its anti-catabolic effect. As it will still bind some insulinase, the enzyme availability for steroids will not be optimal either. Anabolics will lose some of their potency.

What is important to understand is that past a certain dose, anabolics will provide their own antidote against muscle growth. The only solution (beside using less steroids) is to increase insulinase level.

At least two factors can accomplish this feat:

The first one is insulin itself. The higher the insulin level is in a target organ (muscle for example) the higher the insulinase level will be. You would expect that the body would detect the shortage of insulinase for insulin and so produce more insulin (or more insulinase).

Unfortunately, this does not seem to be the case. While insulinase is crucial for the anti-catabolic effect of insulin, it does not seem as important for glucose disposal.

Insulin's main function is not to assist in muscle growth but to control glucose homeostasis. As a result, it is likely our body does not really care about a relative shortage of insulinase. In any case, we are left with a less than optimal equilibrium. It is up to the bodybuilder to react to this imbalance.

One way of increasing insulin secretion is to eat more, but you can only do so up to a point. You cannot increase your carb intake in parallel with the amount of steroids without getting too fat. Another solution is to use drugs to add or to stimulate insulin secretion. This way you get the insulin without the excess of calories.

In any case you now understand why steroids work better while on a high calorie diet while they lose their potency during a diet or a shortage of insulin.

Here is a way of "artificially increasing insulin level": One dose of long acting insulin first thing in the morning (this is the only injection). Before each meal (except the pre-workout one), take a sulfonylurea (an oral anti-diabetic drug which will boost food induced insulin secretion ). I like Glipizide because of its short half-life. In case you experience hypoglycemia, you know it will not last. This is the main problem with the long acting sulfonylureas. When you are hypoglycemic, you try to compensate by absorbing carbs. But the drug will make your pancreas secrete even more insulin before the carbs can hit the blood. It makes the hypoglycemia worse - not better.

In case of problems, make sure you get some ready-to-inject Glucagon (sold as "insulin emergency kits" in drugstores). An additional benefit of the Glipizide is that it induces the release of GH on top of insulin which is beneficial for non diabetics.

This is a nice way to fix the reduced anticatabolic property of insulin. Unfortunately, this will not yet provide the optimal amount of insulinase to have steroids work better.

We said that training was the third key ingredient in this synergy. This is because training can stimulate insulinase activity. Not any exercise will do. The traumatic ones inducing muscle soreness are the most effective. It is the factors inducing soreness which will trigger this increase in insulinase.

On the other hand, you do not want to create too much soreness as it will temporarily reduce the effects of insulin and androgens by impairing their effects at the level of their respective receptors. What you want is mild but frequent soreness along with some very frequent pumping sessions.

Do not forget both androgens and insulin circulate in the blood. The more blood you get into the muscles (and the longer it stays), the more your muscles will be "drenched" in those two hormones. Please note that insulinase is produced locally in the trained muscles only. It does not circulate into the blood.

Why Insulin is so great?

Obviously, there's a correlation between the amount of circulatory infulin and muscular anabolism..More abviously is the fat that many chemically enhanced athletesself-adminsiter exogenous insulin for this reason..

Exogenous insulin is possibly the most anabolic substance employed by hardcore athletes (and likely the most dangerous) This is not necessarily due to the direct action of insulin itself upon muscle cells, but largely due to the fact that there is a synergy between insulin and almost all others anabolic substances.

Here is the good part..

Our bodies produce a protein called SHBG (sex horomone Bingind Globulin) that deactivates circulationg androgens.As a rule of thumb 98-99 % of out circulation test is inactive due to being bound by SHBG, and to a lesse degree, albumin. This means only about one to two % of our circulation testosterone is free or active to do the anabolism thing with muscles cells receptors.

After 10-14 days, the new increase in testerone is mediated in effect by SHBG..So the body reacts to high test levels by producing more SHBG, thus decreasing the amount of free androgens...

Now when insulin is introduced there is a decrease in SHBG production. In addition, there is a freeing effect upon existing SHBG that results in an increase in free androgens..(Quite a puls if a athlete is to employ AAS at the same time..This results in a certain syngery between the AAS and the insulin that in turn results in much greater growth potential than would be realized if either was used alone.

...galera ai relata diversos estudos e até experiências vindas de usuários e bb, como podem ver há mais de um estudo para cada tópico, então, antes de tomarem qualquer atitude, por precaução, leiam ambos antes de tirar uma conclusão... deixei em negrito os tópicos importantes, até para se localizarem melhor, abraços.

[NiggaFat 55]

do que adianta postar em ingles se grande parte do povo não sabe ler, e se saber provavelmente não vai ter pasciencia de ler?

[rmpersonal 692]

do que adianta postar em ingles se grande parte do povo não sabe ler, e se saber provavelmente não vai ter pasciencia de ler?

preguiça mode on?

[MOTD 353]

estão desenterrando textos em rsrs!

[rmpersonal 692]

estão desenterrando textos em rsrs!

Hj eh o segundo q eu ressuscito. to pensando em add slin no prox protocolo, ai resolvi revisar certas coisas.